Biology and Treatment of Eosinophilic Esophagitis

Dietary Treatment of Eosinophilic Esophagitis

Diagnosis and treatment of eosinophilic esophagitis

Eosinophilic esophagitis (EoE) is a new disease. It is caused by a T-helper type 2 cell response to food antigens in contact with the esophageal mucosa. Although no single feature defines EoE, a constellation of compatible demographic, clinical, endoscopic, and histologic findings establish the diagnosis. Children present with symptoms and endoscopic patterns characteristic of inflammation, whe...

Eosinophilic esophagitis -- clinical manifestations, diagnosis, and treatment.

Eosinophilic esophagitis (EE) is a chronic inflammatory, immunoallergic disease of the esophagus that represents the most common eosinophilic gut disease. Understanding and diagnosis regarding this condition have greatly increased in recent years, particularly in Europe and North America, in parallel with other allergic disorders. It consists of dense esophageal infiltration with eosinophils in...

Treatment of eosinophilic esophagitis by dilation.

Treatment options for eosinophilic esophagitis (EoE) include drugs, diets and esophageal dilation. Esophageal dilation can be performed using either through-the-scope balloons or wire-guided bougies. Dilation can lead to long-lasting symptom improvement in EoE patients presenting with esophageal strictures. Esophageal strictures are most often diagnosed when the 8- to 9-mm outer diameter adult ...

Mepolizumab in the treatment of eosinophilic esophagitis

Eosinophilic esophagitis (EE) is a clinical entity characterized by eosinophilic infi ltration limited to the esophageal epithelium without signifi cant eosinophilic infl ammation of the remainder of the upper gastrointestinal tract mucosa. It can occur in isolation or as part of an atopic spectrum together with asthma, allergic rhinitis and/or atopic dermatitis. EE was fi rst described in the ...